What is "dele" means in Portuguess? How do use it?

"dele" it is a pronoun in portuguese.

Ex: Este carro é dele.

Dele is a possessive pronoun, and is the result of the contraction of "de" (= of) and "ele" (=he). So, on the example above, "Este carro é dele", it means that he is the owner of that car.

Other examples: De quem é esta caneta? (Whose pen is this?) - Esta caneta é dele (This pen is his); Esta é a casa dele (This is his house).