Expenditure defines as payment of cash or cash-equivalent for goods or services, or a charge against available funds in settlement of an obligation as evidenced by an invoice, receipt, voucher, or other such document. Expense tells about something spent to attain a goal or accomplish a purpose: an expense of time and energy on the project. The money spent or cost incurred in an organization's efforts to generate revenue, representing the cost of doing business.
Expenditures would usually be used to refer to chunks of money companies spend for certain things: such as "capital expenditures."
Expenses is more often used to refer to money individuals spend, such as "business trip expenses," "gas expenses," "food expenses," etc.
expenses=individual, expenditure=larger