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Ano sa Tagalog ang "How are things?"

if you are referring to a specific person, you can either use "Kamusta ang kalagayan mo?" (How is your condition) or "Kamusta ka?" (How are you?). If you are asking 2 or more persons, you can use "Kamusta kayo?" (How are you all?) or "Kamusta ang kalagayan ninyo?" (How is everybody's condition?)

we usually just say "kamusta" or "kumusta"?

o genki desu ka? ~> " how are this? " how are you? ~> musta? / kumusta ka ??