源
yuán
①水流起头的地方：河～│泉～│发～│～远流长│饮水思～。
②来源：货～│资～│病～。
③（Yuán）姓。
The collocations you presented may be correct, grammatically; but not pragmatically...c'z they sound weird to native speakers, like me.
源can be collocated with substatiated things, as the above examples, and unsubstatiated objects, like, 电源， 根源，your 痛苦源（though 痛苦的源头is better）.
I suggest you doing some basic readings on Modern Chinese morphology to figure out the rules for Chinese phrase and it will be much easier to learn plenty of phrases after you know the single character!
For example, 源泉 and 泉源 are almost different things though the characters are the same.
