Undecided questions
What does 是非感[shìfēigǎn] mean??

Is 是非感 a noun??
Never heard of that phrase before.

Is there any adjectives for 是非感??
Again never heard of it

What is 良心[liángzhī] ??
Can we say that, a person who has 是非感 or 良心, is 负责 in his work or life??
良心 means conscience, 负责 means responsibility. Having a good conscience doesn't necessarily mean that you are responsible and vice versa.

I think that many of Chinese native speakers hadn't met a word like "是非感" yet.
But I suggest it means "the sense of justice", in Chinese, it's called "正义感".

“良心” is a word for the kind of virtue of humankind. People with "良心" will not do harm to others while they are doing their own business. In China, this word is commonly used to describe a entrepreneur who manufacture the product that will not have a bad effect on the consumers(especially food manufacturers for you might know that the food security problem in China= =||)
Example: 这是一位有良心的企业家

We can say a person has 正义感 in his life (especially while comfronting some kind of criminal behaviors.)
We can say a person is 负责 in his life.

there is no such thing as 是非感
it's better if you give a complete sentence where these symbols are used

良心 = liáng-xīn = conscience

负责 fù-zé = being responsible as having the duty