I'm not sure what it meant in The Secret Life..., but Larry, Curly and Moe were a comedy team called The Three Stooges. See http://en.wikipedia.org/wiki/The_Three_Stooges

This was an "answer disguised as a question" the underlying meaning was, "Answer this question, and you will know the answer to your question. It is assumed that the original questioner knew that "Larry, Curley, and Moe" we're silly and maybe a bit crazy and stupid to the extent that is was comedic. They were not exactly " Right in the head" , therefore the answer would have been that the person that the original questioner asked about is " not right in the head" People sometimes use this form of communication to lighten the conversation by pretending not to answer the question,and speaking I'll of someone, when really they are answering the question by asking a question that has a comparative answer to the one they want to give but are reluctant to.