Much and many are simply words that have to do with a large amount of an object. If the object is a "Count noun" you use "many" as in "Many bananas" or "Many people". If the object is a "non-count noun", then you use "much" as in "much time" or "much emotion". A good test for this would be objects that you can put numbers in front of. For instance: You can say "I have 3 bananas" but you can not say "I have 3 time".
Regardless of whether the sentence is a positive, negative, or question sentence, it is okay to use both "much" and "many" as long as they are used with the correct nouns.
Hope this helps :)