A sentence like this really emphasizes how a comma, or lack thereof, can make a sentence more readable.
Because the antidote to this problem of the undisciplined pursuit of more[,] is the disciplined
pursuit of less but better.
The comma adds a pause to mark the end of the phrase "the undisciplined pursuit of more." The lack of a comma before "but better" notes that it is part of a larger piece, "the disciplined pursuit of less but better."
This was probably hard to pick up from a podcast, but hope this still helps!