How do you say "Good luck" in Cantonese?
for example, your friend is exercising so she can lose weight. How do you say "You can do it/Good luck!" in Cantonese?

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你實得嘅！/你實掂啦！means you can absolutely do it! 
祝你好運！means good luck to u!

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你掂嘅.大概就咁嘅意思啦

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I think 祝你好運 in this case might sound a bit unnatural, almost sarcastic, in fact it's mostly  used in written form; usually a 加油呀!would be enough =)

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你實得嘅！

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祝你好运~~