It could be. It depends on the context.
"Try to be awake by 8:00 am" means "Try to wake up by 8:00 am." In this case, they are the same.
"The new show airs at midnight tonight. Try to be awake, so you can watch it with me." This means "Try not to go to sleep before midnight." In other words, "Try to stay awake so that we can both watch the show."
"Try to be awake during class" could mean "Try not to fall asleep during class" or "Try to be alert and pay attention during class."
(Edited to add: Also, I agree with Miguel, most native speakers don't usually say "try to be awake." I've heard it, but it's much more common to hear "try to get up"/"try to wake up" and "try to stay up"/"try to stay awake"/"try not to fall asleep.")