how should i say that:
it's something that i want to dedicate my whole life with ( can i say like that, when i want to do it all life? Or dedicate is not a good word in this sentence) or how to say something like that to sound like a native speaker

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As everyone already said, you can say "it's something that i want to dedicate my whole life to." You're essentially saying that you want to commit yourself to a goal, cause, or a way of life.

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"it's something that i want to dedicate my whole life to." or you can also use devote here.
"it's something that i want to devote my whole life to"

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Hi Dedicate is perfect.  But, dedicate my whole life to, not with.

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Hi Yuril ,

If I interpret you correctly...
You can use the word 'dedicate'.. "My lifeworthy dedication"  "My Lifelong dedication". "My dedication in Lifework. There are other options and words as well, that may befit but...

I hope these are sufficient :)

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