Practice is a noun. Example 1: I went to the doctor's practice. Here, "practice" is a location - doctor's surgery. Example 2: For studying, my usual practice is to answer all the questions first. Here, "practice" is a routine NOTE and exception : this is also the US spelling of "practise" (see below) Practise is a verb. Example: I like to practise playing the piano each day.

I believe the main difference between the two is that 'practice' is mostly used as a verb or noun in the US and it's incorrect when used as a verb outside the US, while 'practise' is mostly used as a transitive in Britain, Canada, Australia, New Zealand and Ireland. When you see two similar words that are confusing you, I highly recommend you compare them at wikidiff.com. Here's the web's explanation of the difference between the two words: https://wikidiff.com/practice/practise. Hope that will help. :)

Practice is a noun. Refers to the act. Where as practise is the verb that means repeating an action.