No, we use "do you [verb]" for habitual actions. It doesn't make any sense to ask whether you habitually have one good weekend.
If you're asking about the present, you can say "Are you having a good weekend?" For a weekend that's already past, you have to ask "Did you have a good weekend?"
If, for some reason, you wanted to ask whether someone usually has good weekends, you'd need to use the plural "weekends." It would be grammatically correct to say something like "Do you usually have good weekends?" However, it sounds rather strange.