Stricktly speaking, it is not a comeplete sentence.
Sometime it means "how are you" or "Are you fine?"(1)(2), other times means how are things you deal with going, and in some situation it means "can you do this?"(3)
(1)It is a long time you have not see your friend. You meet him casually, you say, hen3ju3bu2jian4ni3zen3me0yang4?
(2)Your friend sufferd a lot for his girl friend leaving him, and he is so upset and got a sick.One day you came across him and you acknowledged to him, say, ting1 shuo1 ni3 sheng1bing4le0,ni3 zen3me0yang4?ni3hai2hao3ma0?
(3)Your company got a special program for business, and the manager ask you, wo3men2xu1yao4yi1ge4ren2 fu4ze2zhe4 ge4 gong1zuo4, ni3 zen3 me0 yang4?