Yep, you can. You can usually consider 'what to do' (and similar structures) as a noun.
Although if "what to do" is the title of an article, I expect the article to tell me how to do it. If I was making a topic on italki describing how to use articles, I could name it "How to Use Articles", but if I wanted to ask about how to use articles, I'd name the topic "How do you use articles?" instead.