These are basically interchangeable, but I think there is a subtle difference. "Want in a ___" means a person or thing simply has the properties the speaker desires. "Want out of a ___" means that the person or thing can actively can give, provide, or deliver something to the speaker.
Ex. 1: The things I want in a car include a manual transmission, heated seats, and a powerful engine.
Ex. 2: The things I want out of a car include a feeling of safety, reliability, and power.