As a native speaker, I would use the word "nonsense" to describe words that were foolish or silly.
For example, when a friend is complaining about having to get the whole car repainted because of one small scratch,
I might say, "What you are saying is nonsense. Just repaint the scratch".
The word "senseless" is often used to describe the extreme actions of people that have no feelings or conscience.
For example, when describing a murder or bombing, many people say, "It was a senseless crime".
I hope this helps