Basically it means that if you can apply those tools to your passion (your work, presumably), then you will be ready to succeed (in a position to crush it).

The meaning and context is not clear. What is "it"? "passion to the unbelievable reach and power of these tools" is not clear. It's impossible to help you without further clarification.

Social media give entrepreneurs and businesses an unprecedented chance to engage with their customers and communicate their message. Those who can harness their passion to the unbelievable reach and power of these tools are in a position to crush it on a level the world has never seen.

Hello. This is part of a book by Gary Vaynerchuk. I will provide further details.