Literally, it means 'can you think of anything that is not like this?' Similar to "tell me something I don't know", or "You don't say?". In other words, what that person said to you is obvious and you're being sarcastic about it, or else you simply don't care if what you're is obviously good (bad, dangerous, stupid etc). In that context, it can be something like "to hell with what they say".
A:Don't eat that it's bad for you.
B:Like what isn't.
...Followed by devouring whatever it was you weren't supposed to eat : )