- you go down the street and stumble a person, then you say: "lo siento" or "Disculpe" or "perdon"
- you throw coffee on a person, then you say: "lo siento" or "Disculpe" or "perdon"
- in some regions "perdon" is used in more serious context, for example, if you are if you are unfaithful to your partner you, then you say "perdon" during next 12 months.
- I would say from the more soft term to hard term: 1. Disculpe 2. Lo siento 3. Perdon
- when you are eating with a group of friends and you left the table, then you say: "con permiso". You never say: "Disculpe" "lo siento" "perdon", at least that you say: "disculpen, me tengo que ir" "lo siento pero debo irme"