it means 至少，无论如何 anyhow

At least = 至少；起码 Replace at least with 至少；起码 in your examples, then it's the way how they are used.

at least=至少/起码We played golf at least twice a week. 我们一星期至少(起码)打两次高尔夫球。 At least I know now.=至少(起码)我现在知道了。 At least he finally told you.=至少(起码)他最后告诉你了。 At least its not raining.=至少(起码)现在不下雨。 At least I tried.=至少(起码)我尝试过了。

不管怎样 or 无论怎么 or 至少

你在学习中文吗？