hi, 直譯 - there is no medicine that can save her 。。 我們不能把一個中文成語直接翻譯成英語, （但我們一定會懂得你的意思） 我們有一個成語: "up a creek without a paddle" 還可以用別人提出的相同英語句子, other common expressions to indicate someone is in an unlucky or terrible situation: - she's doomed (severe) - she's out of options (lighter) - she's out of luck - nothing can save her now - she's "between a rock and a hard place" - she's screwed (impolite, vulgar, slang) - she's f-----d (impolite, vulgar, slang)

如果是字面上的没药救了（医院/药物/医生） She/he is incurable. incurable disease （绝症） 如果是指脾气，性格，人品什么的，（我估计你是说这个吧）觉得下面的可以用： She/he really is hopeless. She/he is completely helpless. She/he is really impossible.

She/He is really helpless would be the translation in that sentence. 无药可救了 means both "helpless" and "incurable". Ex: His medical condition is incurable. She is such a helpless person. (your example)

My figurative translation: Nothing can save him/her. Literal : No medicine can save him/her.

She/He is hopeless.