I doubt there are any native speakers use that expression on a *daily* basis, but it's certainly not an uncommon expression. The important thing is to use it in the right context - for example if you are describing to somebody a method to produce or achieve something you might say "You go through these five stages, which I will tell you about in detail, and then Bob's your uncle."

American English: we only say it when we're pretending to be British. That isn't something that most people do every day. But, you do you.

Thank you for all your comments. It's been interesting to hear your opinions!

If somebody has an uncle named Bob, why not?