Yes, and it's a big one. Self-reliance is when you depend on yourself, your parents don't give you money, you work hard and you don't rely on some one else to help you. Self-confidence is a feeling, too much of it can make you seem cocky or arrogant or narcissistic , too little can make you seem anxious/worried/shy. You can be confident that you are self reliant but that doesn't necessarily mean that people see you as a self-reliant person