1) if a place is very tight, than you can feel claustrophobic. Like if yomeone will put you in a very small box and close this box, so you wont be abe to move and breath very well.
2) You are fed up with something if you cant take it anymore. Imagine you would have to eat the same food for 1 year, listen to the same song for one year, see the same movie and so on. After some time this might make you angry and upset. Than you reached the state of fed up.
I hope these example help you to understand these words better.