Hi Sharon, number 1 and 4 are correct. In Italian the sex of the person speaking doesn't make any difference here. What matters is if the friend is a male or a female. All the other elements in the sentence: article (il/la), possessive (mio/mia) and adjective (italiano/italiana) only match the noun AMICO/AMICA. So you'll say: La mia amica è italiana Il mio amico è italiano

Thanks a lot Rudy for your help. I understand now. Grazie mille!

If you are male or female doesn't matter, because the subject of the sentence is the friend. MY FRIEND is italian----> If the friend is a girl : La mia amica è italiana. ----> If the friend is a boy: Il mio amico è italiano.