Is my boss a hoss or muckety-muck?
I heard in a TV series a person being called a "hoss". In a dictionary it's translated like a "big boss" or "gangster boss" or a cool guy respected by the other group members. So, what dose it really mean? Is it used like mockery similar to a "high muckety-muck"? If my friend got a promotion, should I call him a hoss? Can I say "he is our boss-almighty"?

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Not as commonly used.  Probably make u sound cool.  You're basically calling him the manliest bad ass ever.  If you call him "your boss almighty"  as English is not your first,  might sound cute or funny.

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No idea whether this new-fangled thing is related, but years ago the was a TV series called "Bonanza" which included one son who was big and called "Hoss" by all.
Have not heard this since the TV series finished. It was a great show it ran from 1959 to 1963 according to wikipedia.
Never heard the other term.

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You can use hoss but it’s not mocking, it’s just slang. It is used more for a big physical appearance and dominance (like a horse). Like watching a guy work out, “What a hoss”.

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What can I use then instead of "muckety-muck" when I talk about a person with power who I dont't really like?

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Probably off topic but Hoss was one of the main characters in an old Western series called Bonanza.  I assume it was because he was a big guy like a horse.