"When's the last time you ate?" is natural. It's exactly what I would expect a medical technician to say before a glucose test.
I live in Medford, Massachusetts, USA, population 62,000. However, you will see that it is a suburb of the big city of Boston, Massachusetts. From Medford, you could go down the Mystic River, into Boston Harbor, and out into the Atlantic Ocean. You can use Google Street View. As in most of the northern states in the United States, you will see that many people live in individual two-story houses, made of wood, with a basement under the first floor and an attic over the second floor.