It's used generically in many areas. Only with a sexual context would it give you any worries.
The nail missed the stud and penetrated the desk. Th epeneration was about 1cm.
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We've failed to penerate the Turkish market to any significant degree.
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The latest offensive by the rebels was to penetrate 400km into the goverment area of ...
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All ok in normal conversation.
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Also used as a techical word regarding sexual practices.
You claim he molested you: I understand, but we need to know whether there actual penetration?
Take care with this meaning :)