حجرة also means room and chamber. so what is the difference between them? i may say the difference is ghurfah used for rooms that imposed different meaining to each one to describe them, like bedroom, bathroom, living room.... as we see all of them rooms but purposes of use are different. hojrah is used for the rooms that all descibed for the same purposes.
native spaekers may know better, i am not a native araic speaker. but this is my opinion