what does it mean? VS what does that mean?
what is the difference ??

and

which do you use between the two ??

please choose either one of those two.

Question

what does it mean? VS what does that mean?
what is the difference ??

and

which do you use between the two ??

please choose either one of those two.

Answer

They mean the same thing but you tend to use "What does that mean?" when you want to know the meaning og something in a book.