Your use of “wish” is correct, and the grammar is generally good in your sentence. The word “profundity” seems odd to me. For one thing, “depth” might be a better synonym, for another, “crest” and “depth” are opposites, so you may need a stronger connecting phrase, or you may want to choose another word entirely. Another thing: You’ve actually succeeded to well at sounding “natural” — to “wish someone all the best” is so commonly used that it is not really a very strong phrase. Perhaps something more original would better express your feelings. One more thing: “University” can take the pronoun “it”, or (usually in UK English) “they”, but in your sentence, I’d be inclined to say “she / her”. Maybe I’m just old-fashioned — let’s see what other native English speakers think.