To me, yes.

If the question is simply "How about you?" or "What about you?", then it is exactly the same. It is used to ask people what they are doing, their opinion, how they are feeling, etc. after you or someone else answered the same question.

Example:

Albert asks, "Brandon, are you traveling this summer?"

Brandon replies, "I'm planning to go to Spain this summer. How/What about you, Charlie?"

Charlie says, "I'm going to be working, so I can't travel."

However, if "how about" and "what about" are the start of a longer sentence, they have slightly different meanings. "How about..." is used to make a suggestion.

Example:

Arthur says, "How about we watch a movie?"

Bella replies, "Sure, great idea!"

"What about..." can be used for suggestions that we are not sure about.

Example:

Antonio says, "My phone isn't working. Do you know how to fix it?"

Beatrice suggests, "What about turning it off and on again?"

(In this example, Beatrice is not sure that turning the phone off and on again will work, so she says "What about...")

I hope this was clear. If you have any questions, don't hesitate to ask!