How do you use the word "with" in Mandarin Chinese?
I've heard many uses but I cannot distinguish which is the proper way to use it. If you could explain to me how to use "with", that would be helpful. Thanks!

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There are many meanings of "with" in Chinese in all kinds of situations.
It means "带有“、“和” or "伴随” and etc.

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Hi, I'd like to be language partners on italki.
hi, my name is Marcelo, eu sou brasileiro, posso te ajudar no portugues, my skype is marcelomirmar68, please add me, bye bye

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和，跟。最贴切吧

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which "with" are you talking about -- 与? 和? 跟?

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I can't abide people with no sense of humor.
我讨厌和没有幽默感的人打交代。

Let's start with the more easily addressable issues.
我们先从较容易的问题着手。