To come up with means to find a solution/ idea. If you want to use it, you can do so every time that you need someone to make a suggestion. For example, you are meeting with someone, and you can say: I have no idea where to go. Can you come up with suggestions? If you need more help with conversational English, please feel free to contact me, and we can practice.

The same question was asked about four hours ago. You can have a look at the answers: http://www.italki.com/question/285916