"She will lose it" - What does it mean? I dial him as fast as my fingers will allow, praying that he hasn't called my mother yet.He doesn't pick up, but I text him assuring him that I'm okay and there is no need for him to call my mother. She will lose it if she thinks something happened to me on my first weekend of college. it's from a book. I don't understand what "she will lose it" means.. something like "she won't feel well"?