There are two main meanings.
The first is as a verb 'to orient'. This means to turn something in order to achieve a specific goal. For example, we orient a ship to sail in a specific direction. We might also orient the things in a room in order to make it pretty. The noun form of this verb is usually 'orientation'. When you orient something, you change its orientation.
A second use is as a proper noun 'The Orient'. This refers to anything considered 'Eastern' - so, most things outside America and Western Europe. Most usually this means Asia. For example, many Chinese or Asian food restaurants are described as being 'oriental'.