#1 is correct, #2 doesn't make sense. You can "strip someone of" an intangible quality, like their power, freedom, or dignity. You can't "strip off" an intangible quality from someone. However, both can be used to talk about removing something tangible, like in the example below: You'll also notice that the object/wording changes between the two. They stripped the bark off of the tree in the process of cutting it down. (strip x off of y) They stripped the tree of its bark in the process of cutting it down. (strip y of x) There's not a big difference between the two in my opinion. In most casual situations, I think "stripped off of" is more common.