Wind,
The literal meaning of "to have your money tied up in futures" means "to have your money promised to pay future contracts."
--Penny has a lot of her money tied up in promiscuity futures.-- This is only a play on words and does not have the literal meaning of "tied up in futures". It means rather that Penny is spending her money on promiscuity now with hope of a future gain. This gain would most likey be a future husband.
If you would include more context in your questions they would we easier to answer. I searched for the episode that you quoted from and you can see from the context that Penny is indeed hoping through promiscuity to gain something. I hope she is looking for a mate, but perhaps she is just being promiscuous for the free drinks. :) What do you think?
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“Let me ask you, when you get back out there, are you wearing this?” – Mrs. Cooper
“Look, it’s super cute on. That top has paid for itself in free drinks like ten times what it cost.” – Penny
“Yes, Penny has a lot of money tied up in promiscuity futures.” – Sheldon
“Hun, do you think maybe the reason you’re having trouble finding a guy to settle down with is because you’re letting him ride the roller coaster without buying a ticket?” – Mrs. Cooper
“Oh, they don’t always get to ride to roller coaster. Sometimes they only get to spin the teacups.” – Penny