I'm guessing you want to make an interrogatory. Let's say you're asking if there is someone here who knows CPR. 1. Is there anyone here who knows CPR? 2. Is anyone here who knows CPR? The first one is a sentence. The second one is a clumsy and odd-sounding sentence. You should study sentence structure.

No, you can't omit the 'there'. The word 'there' is the subject of the sentence, sometimes known as a 'dummy subject'. If you don't include it, the sentence has no subject. Compare these two sentences: Is anyone hungry? = The subject is 'anyone'. Is there anyone who speaks French? = The subject is 'there'. You can't omit it.

- Is there anyone here who ...? >ok > Is +at this place+ anyone here who .. - Is anyone here who ...? >X . "Is" means " be" and it means for certain who he is , and "anyone" does not have the certainty to go together

I wouldn't say it's wrong, but the second one sounds informal to me. I would say you CAN omit it if you want to.