очень зависит от контекста, но раз это культурный феномен и немножео игра слов то я бы это переводила описательным методом, например "he is easily accepted and understood by those people who are different / far from him, but those, who are near him, don't really get him"

At home among strangers, A stranger among his own

Google gives the translation "strangers among you", but I guess your intended meaning is more similar to "alone in a crowd".