‎To make a best friend is not easy.
Making a best friend is not easy.

What’s the difference between those two sentences？

Question

‎To make a best friend is not easy. 
Making a best friend is not easy.

What’s the difference between those two sentences？

Answer

For me, in terms of meaning there is no difference at all.  I would say "making" is probably more usual in speech and in writing.

Answer

"To make a best friend is not easy" doesn't sound as natural, especially in casual speech. "To make" is the infinitive and does express the same idea as "making", but most native speakers would use "making" in this sentence, and in any similar structure.

Another example:
"My least favorite task is washing the car."
vs.
"My least favorite task is to wash the car."

We often won't naturally use the infinitive, but the two forms carry the same meaning.

Answer

1. “To make a best friend is not easy.”
This sentence uses the infinitive form (“to make”). It’s grammatically correct, but it feels slightly more formal or philosophical—almost like a general statement.

2. “Making a best friend is not easy.”
This version uses the gerund (“making”). It’s more natural in modern English, especially in conversation or informal writing. It sounds more fluid and typical of native speech.

Alternative (More Natural):
“Making a best friend isn’t easy.”
or
“It’s not easy to make a best friend.”

Expert Tip:
Use gerunds (–ing forms) when talking about real-life activities in a general or familiar way. Use infinitives (to + verb) when you want to sound more abstract or formal.