I pronounce it eye-talk-eye. This is because I read the 'I' before and after 'talk' as the English first person pronoun. This makes sense to me as it expresses two individuals talking together. But that's just the feeling I had when I first saw the word.

Interesting question. I will say eye-talkie because it sounds more natural to me.

Tangent: How do you pronounce IKEA?

Eye-talky as in "I talk" and perhaps "walky-talky" (walkie-talkie) seems natural to me.

idk. I call it "eye-talk-eye"