"You and I" is used when it is the subject of the sentence: You and I (we) went to the movies. "You and me" is used when it's the object: They invited you and me (us) to the party.

You and I-- subject you and me--direct or indirect objects. you is easy- always the same, subject, indirect or direct object. you and me are going to the store. Yes nous Americains le disent, mais ce n'est pas correcte You and I are going to the store. Dis cela, est correcte

Yes, James is right. “You and I" is used when it's the subject of the sentence. "You and me" is used when it is the object of the sentence. You and I are eating ice cream. This ice cream is for you and me to eat.

Thank you! All is clear now :]