Hi there. This is a joke about menopause. That is when a woman stops getting her period. Symptoms include hot flashes. Some women take estrogen patches to relieve the symptoms of menopause. If it expired (doesn't work anymore) they will get hotflashes. https://www.menopause.org/for-women/menopauseflashes/menopause-symptoms-and-treatments/the-experts-do-agree-about-hormone-therapy