Yes... if you want to wake up the next morning cursing the day you were born =p Sometimes, you could put some tequila on the bottom of a large glass full of beer, with the "shot" (i mean, the little glass that you use to drink tequila) and then drink it. O_O hahahaha... but, usually, no one wants to do that, so it's normally used as a 'consequence' when you are playing something with your friends... like JENGA ! Whoever makes the tower fall, drinks it !!!

Any spirit can be drunk with beer. And each method has its own special name. ^^ But in general, if you drink a tequila the follow it with a beer, the beer is called a "chaser". However if the glass of beer is very large and you drop the tequila into the glass and drink it all together, the general name is "depth charge".