It's highly unlikely you'd use "made" with "worst" as an adverb. Much more likely is "You made it worse," as in, "you made this situation worse rather than making it better" (here, "worse" is an adjective, not an adverb). It is possible that you might use "worst" like this:
You made it the worst. (superlative adjectives like worst and best need to have "the")
You made it the worst day ever.
However, "worst" can also be an adverb:
The first singer sang best; the third singer sang worst.
Since when "best" and "worst" are used as adjectives they need "the" before them, you'll often see this happening with the adverb, but it's not necessary:
The first singer sang the best; the third singer the worst.