You can say that. Other ways to convey the same thing would be: "He has dedicated many hours on his research." "He has spent many waking hours on his research." "He spent a lot of time on his research." "He spent a long time on his project." "He put a lot of energy into that project."

An english person would not say "He has paid tremendous effort in his research." It would would be either: "He has made a tremendous effort in his research." or "He has made tremendous efforts in his research." "He has buried himself in his research." is fine except for the typo (himeself)