Hola como estas means Hi how are you
bien e Tu gracias means not that bad you and thank you
how to say please in Spanish is Por favor
after someone asks you a question and you answer it always say gracias

Question

Answer

Hola, ¿cómo estás? = Hi, how are you?

Bien, ¿y tú? = Fine, and you?

Please = Por favor.

After a question or a favor you can answer:
Gracias = Thanks!
De nada = You are welcome
Es un placer = It is a pleasure
Con gusto = With pleasure, gladly

Un saludo desde Medellín, Colombia.

Answer

bien, "Y" tu? gracias.

I didn't really get the question, but everything is correct except for the above sentence.