Well, the grammar of your question is not right, so I am guessing that you are asking if you are handsome-- or maybe you are asking if someone else is handsome. Handsome is an adjective that is applied to men or objects that you might think of as having a masculine character. Girls and women are pretty or beautiful, but not handsome. Men are not pretty or beautiful. They may or may not be handsome, and usually they don't care as much about it as women-- they realize that handsomeness is only skin deep.

What do you mean by "what me is handsome"? Do you mean "Am I handsome"?